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human CYP3A7 Over-expression AAV

Name 
AAV-h-CYP3A7
Cat No 
AAV-206507
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CYP3A7.

AAV-206507
AAV-h-CYP3A7

Ready-to-use AAV expressing Human CYP3A7 (cytochrome P450 family 3 subfamily A member 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CP37; CYPIIIA7; P-450(HFL33); P-450111A7; P450-HFLA
Description (Vector)
CYP3A7 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. CYP3A7 is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced. CYP3A7 undergoes readthrough transcription with the downstream CYP3AP1 pseudogene, resulting in an isoform with a novel C-terminus, as represented in GeneID:100861540.
Gene ID
1551
Gene Name (Vector)
cytochrome P450 family 3 subfamily A member 7
Gene Symbol
CYP3A7
HGNC ID
HGNC:2640
ORF Size (aa)
1512
ORF Size (bp)
1512 bp
RefSeq ID
NM_000765
RefSeq Synonyms
NM_000765, BC067436,
Species
human
UniGene ID
Hs.111944

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.