human CTSK shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CTSK.
shAAV-206273
AAV-h-CTSK-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CTSK (cathepsin K). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CTS02; CTSO; CTSO1; CTSO2; PKND; PYCD
Description (Vector)
CTSK is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
Gene ID
1513
Gene Name (Vector)
cathepsin K
Gene Symbol
CTSK
HGNC ID
HGNC:2536
ORF Size (aa)
990
ORF Size (bp)
990 bp
RefSeq ID
NM_000396
RefSeq Synonyms
NM_000396, BC016058,
Species
human
UniGene ID
Hs.632466
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.