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human CTSH shRNA silencing AAV

Name 
AAV-h-CTSH-shRNA
Cat No 
shAAV-206272
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CTSH.

shAAV-206272
AAV-h-CTSH-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CTSH (cathepsin H). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ACC-4; ACC-5; ACC4; ACC5; CPSB
Description (Vector)
CTSH is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors.
Gene ID
1512
Gene Name (Vector)
cathepsin H
Gene Symbol
CTSH
HGNC ID
HGNC:2535
ORF Size (aa)
1008
ORF Size (bp)
1008 bp
RefSeq ID
NM_004390
RefSeq Synonyms
NM_004390, NM_001319137, BC002479,
Species
human
UniGene ID
Hs.148641

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.