human CTSE shRNA silencing AAV

Name
AAV-h-CTSE-shRNA

Cat No
shAAV-206268

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CTSE.

shAAV-206268

AAV-h-CTSE-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CTSE (cathepsin E). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CATE

Description (Vector)

CTSE is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene.

Gene ID

1510

Gene Name (Vector)

cathepsin E

Gene Symbol

CTSE

HGNC ID

HGNC:2530

ORF Size (aa)

1191

ORF Size (bp)

1191 bp

RefSeq ID

NM_001910

RefSeq Synonyms

NM_148964, NM_001910, NM_001317331, BC042537,

Species

human

UniGene ID

Hs.644082

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.