human CSRP3 shRNA silencing AAV

Name
AAV-h-CSRP3-shRNA

Cat No
shAAV-206166

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CSRP3.

shAAV-206166

AAV-h-CSRP3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CSRP3 (cysteine and glycine-rich protein 3 (cardiac LIM protein)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CLP; CMD1M; CMH12; CRP3; LMO4; MGC14488; MGC61993; MLP;

Description (Vector)

CSRP3 encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.

Gene ID

8048

Gene Name (Vector)

cysteine and glycine-rich protein 3 (cardiac LIM protein)

Gene Symbol

CSRP3

HGNC ID

HGNC:2472

ORF Size (aa)

585

ORF Size (bp)

585 bp

RefSeq ID

NM_003476

RefSeq Synonyms

NM_003476, NM_001127656, BC057221, BC024010, BC005900,

Species

human

UniGene ID

Hs.83577

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.