human CPB2 shRNA silencing AAV

Name 
AAV-h-CPB2-shRNA
Cat No 
shAAV-205878
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CPB2.

shAAV-205878
AAV-h-CPB2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CPB2 (carboxypeptidase B2 (plasma)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CPU; PCPB; TAFI;
Description (Vector)
Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region.
Gene ID
1361
Gene Name (Vector)
carboxypeptidase B2 (plasma)
Gene Symbol
CPB2
HGNC ID
HGNC:2300
ORF Size (aa)
1272
ORF Size (bp)
1272 bp
RefSeq ID
NM_001872
RefSeq Synonyms
NM_016413, NM_001872, NM_001278541, BC007057,
Species
human
UniGene ID
Hs.512937

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.