human DDAH1 Over-expression AAV

Name 
AAV-h-DDAH1
Cat No 
AAV-206691
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DDAH1.

AAV-206691
AAV-h-DDAH1

Ready-to-use AAV expressing Human DDAH1 (dimethylarginine dimethylaminohydrolase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DDAH; DDAH-1; DDAHI; dimethylargininase-1; Dimethylarginine dimethylaminohydrolase 1; epididymis secretory protein Li 16; HEL-S-16; N(G),N(G)-dimethylarginine dimethylaminohydrolase 1; NG, NG-dimethylarginine dimethylaminohydrolase
Description (eCommerce)
Dimethylargininase-1 (DDAH1) hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Therefore, DDAH1 has a role in the regulation of nitric oxide generation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O94760].
Description (Vector)
DDAH1 belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity.
Gene ID
23576
Gene Name (eCommerce)
dimethylarginine dimethylaminohydrolase 1
Gene Name (Vector)
dimethylarginine dimethylaminohydrolase 1
Gene Symbol
DDAH1
HGNC ID
HGNC:2715
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
858
ORF Size (bp)
858 bp
Protein Name (eCommerce)
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
RefSeq ID
NM_012137
RefSeq Synonyms
NM_012137, NM_001330655, NM_001134445, BC033680,
Research Areas
Angiogenesis,Cardiovascular,Mitochondrion
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,developmental_biology
Species
human
Target Sentence
Dimethylargininase-1 (DDAH1) hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Therefore, DDAH1 has a role in the regulation of nitric oxide generation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O94760].
UniGene ID
Hs.379858
UniProt ID (eCommerce)
O94760

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.