human CLIC4 shRNA silencing AAV

Name 
AAV-h-CLIC4-shRNA
Cat No 
shAAV-205454
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CLIC4.

shAAV-205454
AAV-h-CLIC4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CLIC4 (chloride intracellular channel 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
chloride intracellular channel 4 like; chloride intracellular channel protein 4; CLIC4L; epididymis secretory sperm binding protein; H1; huH1; intracellular chloride ion channel protein p64H1; MTCLIC; p64H1
Description (eCommerce)
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells) [taken from NCBI Entrez Gene (Gene ID: 25932)].
Description (Vector)
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells).
Gene ID
25932
Gene Name (eCommerce)
chloride intracellular channel 4
Gene Name (Vector)
chloride intracellular channel 4
Gene Symbol
CLIC4
HGNC ID
HGNC:13518
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
762
ORF Size (bp)
762 bp
Protein Name (eCommerce)
Chloride intracellular channel protein 4
RefSeq ID
NM_013943
RefSeq Synonyms
NM_013943, BC012444,
Research Areas
Cytoskeleton,Mitochondrion
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells) [taken from NCBI Entrez Gene (Gene ID: 25932)].
UniGene ID
Hs.440544
UniProt ID (eCommerce)
Q9Y696

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.