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human CLEC12A shRNA silencing AAV

Name 
AAV-h-CLEC12A-shRNA
Cat No 
shAAV-205401
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CLEC12A.

shAAV-205401
AAV-h-CLEC12A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CLEC12A (C-type lectin domain family 12 member A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD371; CLL-1; CLL1; DCAL-2; MICL
Description (Vector)
CLEC12A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. CLEC12A is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13.
Gene ID
160364
Gene Name (Vector)
C-type lectin domain family 12 member A
Gene Symbol
CLEC12A
HGNC ID
HGNC:31713
ORF Size (aa)
642
ORF Size (bp)
642 bp
RefSeq ID
NM_138337
RefSeq Synonyms
NM_201623, NM_138337, NM_001300730, NM_001207010, BC126291, BC126289, BC063424,
Species
human
UniGene ID
Hs.190519

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.