human DCPS Over-expression AAV

Name 
AAV-h-DCPS
Cat No 
AAV-206666
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DCPS.

AAV-206666
AAV-h-DCPS

Ready-to-use AAV expressing Human DCPS (decapping enzyme, scavenger). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5'-(N(7)-methyl 5'-triphosphoguanosine)-mRNA diphosphatase; ARS; DCS1; DCS-1; decapping scavenger enzyme; epididymis secretory sperm binding protein; heat shock-like protein 1; HINT5; HINT-5; hint-related 7meGMP-directed hydrolase; histidine triad nucleotide-binding protein 5; histidine triad protein member 5; homolog of C. elegans 7meGMP-directed hydrolase dcs-1; HSL1; HSPC015; m7GpppX diphosphatase; mRNA decapping enzyme; scavenger mRNA-decapping enzyme DcpS
Description (eCommerce)
DCPS is a decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. DCPS Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated RNA fragments and 7-methylguanosine monophosphate (m7GMP)[taken from NCBI Entrez Gene (Gene ID: 28960)].
Gene ID
28960
Gene Name (eCommerce)
decapping enzyme, scavenger
Gene Name (Vector)
decapping enzyme, scavenger
Gene Symbol
DCPS
HGNC ID
HGNC:29812
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1014
ORF Size (bp)
1014 bp
Protein Name (eCommerce)
m7GpppX diphosphatase
RefSeq ID
NM_014026
RefSeq Synonyms
NM_014026, BC014532,
Research Areas
Apoptosis,Gene Expression,Mitochondrion,mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
DCPS is a decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. DCPS Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated RNA fragments and 7-methylguanosine monophosphate (m7GMP)[taken from NCBI Entrez Gene (Gene ID: 28960)].
UniGene ID
Hs.504249
UniProt ID (eCommerce)
Q96C86

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.