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human CHI3L1 shRNA silencing AAV

Name 
AAV-h-CHI3L1-shRNA
Cat No 
shAAV-205131
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CHI3L1.

shAAV-205131
AAV-h-CHI3L1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CHI3L1 (chitinase 3 like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ASRT7; CGP-39; GP-39; GP39; HC-gp39; hCGP-39; HCGP-3P; YKL-40; YKL40; YYL-40
Description (Vector)
Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.
Gene ID
1116
Gene Name (Vector)
chitinase 3 like 1
Gene Symbol
CHI3L1
HGNC ID
HGNC:1932
ORF Size (aa)
1152
ORF Size (bp)
1152 bp
RefSeq ID
NM_001276
RefSeq Synonyms
NM_001276, BC039132, BC038354, BC008568,
Species
human
UniGene ID
Hs.382202

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.