human CEACAM3 shRNA silencing AAV

Name
AAV-h-CEACAM3-shRNA

Cat No
shAAV-204929

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CEACAM3.

shAAV-204929

AAV-h-CEACAM3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CEACAM3 (carcinoembryonic antigen related cell adhesion molecule 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CD66D; CEA; CGM1; W264; W282

Description (Vector)

CEACAM3 encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Gene ID

1084

Gene Name (Vector)

carcinoembryonic antigen related cell adhesion molecule 3

Gene Symbol

CEACAM3

HGNC ID

HGNC:1815

ORF Size (aa)

759

ORF Size (bp)

759 bp

RefSeq ID

NM_001815

RefSeq Synonyms

NM_001815, NM_001277163, BC106728,

Species

human

UniGene ID

Hs.11

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.