human DAZL Over-expression AAV
This is an AAV expressing Human DAZL.
AAV-206614
AAV-h-DAZL
Ready-to-use AAV expressing Human DAZL (deleted in azoospermia like). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DAZH; DAZL1; DAZLA; SPGYLA
Description (Vector)
The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
1618
Gene Name (Vector)
deleted in azoospermia like
Gene Symbol
DAZL
HGNC ID
HGNC:2685
ORF Size (aa)
888
RefSeq ID
NM_001351
RefSeq Synonyms
NM_001351, NM_001190811, BC027595,
Species
human
UniGene ID
Hs.131179
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.