human CD3EAP shRNA silencing AAV

Name
AAV-h-CD3EAP-shRNA

Cat No
shAAV-204649

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human CD3EAP.

shAAV-204649

AAV-h-CD3EAP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CD3EAP (CD3e molecule associated protein). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

A34.5; antisense to ERCC-1 protein; ASE1; ASE-1; CAST; CD3e antigen, epsilon polypeptide associated protein; CD3e molecule, epsilon associated protein; CD3E-associated protein; CD3-epsilon-associated protein; DNA-directed RNA polymerase I subunit RPA34; PAF49; RNA polymerase I-associated factor PAF49

Description (eCommerce)

PAF49 is subunit of RNA polymerase I. PAF49/CAST has been shown to interact with activator upstream binding factor (UBF) and plays an important role in rDNA transcription.

Gene ID

10849

Gene Name (eCommerce)

CD3e molecule associated protein

Gene Name (Vector)

CD3e molecule associated protein

Gene Symbol

CD3EAP

HGNC ID

HGNC:24219

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1533

ORF Size (bp)

1533 bp

Protein Name (eCommerce)

DNA-directed RNA polymerase I subunit RPA34

RefSeq ID

NM_012099

RefSeq Synonyms

NM_012099, NM_001297590, BC108889, BC038992,

Research Areas

Epigenetic Regulation of Gene Expression,Mitochondrion,Signal Transduction,Transcription Factor/Regulator

Research Areas (Faceted)

cell_biology,genetics,signal_transduction,transcription_translation

Species

human

Target Sentence

PAF49 is subunit of RNA polymerase I. PAF49/CAST has been shown to interact with activator upstream binding factor (UBF) and plays an important role in rDNA transcription.

UniGene ID

Hs.710495

UniProt ID (eCommerce)

O15446

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.