human CCL4L2 shRNA silencing AAV

Name
AAV-h-CCL4L2-shRNA

Cat No
shAAV-204460

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CCL4L2.

shAAV-204460

AAV-h-CCL4L2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CCL4L2 (chemokine (C-C motif) ligand 4-like 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AT744.2; CCL4L; LAG-1; LAG1; SCYA4L;

Description (Vector)

CCL4L1 is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. This protein is similar to CCL4 which inhibits HIV entry by binding to the cellular receptor CCR5. The copy number of this gene varies among individuals; most individuals have 1-5 copies in the diploid genome, although rare individuals do not contain this gene at all. The human genome reference assembly contains two copies of this gene. This record represents the more centromeric gene.

Gene ID

9560

Gene Name (Vector)

chemokine (C-C motif) ligand 4-like 1

Gene Symbol

CCL4L2

HGNC ID

HGNC:24066

ORF Size (aa)

276

RefSeq ID

NM_001001435

RefSeq Synonyms

NM_001291475, NM_001291474, NM_001291473, NM_001291472, NM_001291471, NM_001291470, NM_001291469, NM_001291468, NM_001001435, BC171864, BC148784, BC146958, BC146944, BC146445, BC144394, BC144393, BC092445,

Species

human

UniGene ID

Hs.661942

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.