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human CCDC52 shRNA silencing AAV

Name 
AAV-h-CCDC52-shRNA
Cat No 
shAAV-204331
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SPICE1.

shAAV-204331
AAV-h-CCDC52-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SPICE1 (spindle and centriole associated protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CCDC52; coiled-coil domain-containing protein 52; SPICE; Spindle and centriole-associated protein; spindle and centriole-associated protein 1
Description (eCommerce)
Spindle and centriole-associated protein 1 (SPICE) has been shown to localize to centrioles throughout the cell cycle and to spindle microtubules during mitosis. SPICE is required for centriole duplication and proper bipolar spindle formation and chromosome congression.
Gene ID
152185
Gene Name (eCommerce)
spindle and centriole associated protein 1
Gene Name (Vector)
spindle and centriole associated protein 1
Gene Symbol
SPICE1
HGNC ID
HGNC:25083
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2568
ORF Size (bp)
2568 bp
Protein Name (eCommerce)
Spindle and centriole-associated protein 1
RefSeq ID
NM_144718
RefSeq Synonyms
NM_144718, NM_001331079, NM_001331078, BC036951,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton,Replication
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
Spindle and centriole-associated protein 1 (SPICE) has been shown to localize to centrioles throughout the cell cycle and to spindle microtubules during mitosis. SPICE is required for centriole duplication and proper bipolar spindle formation and chromosome congression.
UniGene ID
Hs.477144
UniProt ID (eCommerce)
Q8N0Z3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.