human DAGLB Over-expression AAV

Name 
AAV-h-DAGLB
Cat No 
AAV-206578
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DAGLB.

AAV-206578
AAV-h-DAGLB

Ready-to-use AAV expressing Human DAGLB (diacylglycerol lipase beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DAGLBETA; DGL-beta; KCCR13L; sn1-specific diacylglycerol lipase beta
Description (eCommerce)
Diacylglycerol lipase beta (DAGLB) catalyzes the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. I t is required for axonal growth during development and for retrograde synaptic signaling at mature synapses [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NCG7].
Gene ID
221955
Gene Name (eCommerce)
diacylglycerol lipase beta
Gene Name (Vector)
diacylglycerol lipase beta
Gene Symbol
DAGLB
HGNC ID
HGNC:28923
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2019
ORF Size (bp)
2019 bp
Protein Name (eCommerce)
Sn1-specific diacylglycerol lipase beta
RefSeq ID
NM_139179
RefSeq Synonyms
NM_139179, NM_001142936, BC027603,
Research Areas
GPCR Signaling,Metabolism/Metabolic Process,Neurobiology,Signal Transduction
Research Areas (Faceted)
cell_biology,metabolism,neurobiology,signal_transduction
Species
human
Target Sentence
Diacylglycerol lipase beta (DAGLB) catalyzes the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. I t is required for axonal growth during development and for retrograde synaptic signaling at mature synapses [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NCG7].
UniGene ID
Hs.487498
UniProt ID (eCommerce)
Q8NCG7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.