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human DAD1 Over-expression AAV

Name 
AAV-h-DAD1
Cat No 
AAV-206571
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DAD1.

AAV-206571
AAV-h-DAD1

Ready-to-use AAV expressing Human DAD1 (defender against cell death 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
OST2
Description (Vector)
DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes.
Gene ID
1603
Gene Name (Vector)
defender against cell death 1
Gene Symbol
DAD1
HGNC ID
HGNC:2664
ORF Size (aa)
342
RefSeq ID
NM_001344
RefSeq Synonyms
NM_001344, BC009798, BC007403,
Species
human
UniGene ID
Hs.82890

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.