human DACH2 Over-expression AAV

Name 
AAV-h-DACH2
Cat No 
AAV-206569
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DACH2.

AAV-206569
AAV-h-DACH2

Ready-to-use AAV expressing Human DACH2 (dachshund family transcription factor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
DACH2 is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. DACH2 is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
117154
Gene Name (Vector)
dachshund family transcription factor 2
Gene Symbol
DACH2
HGNC ID
HGNC:16814
ORF Size (aa)
1398
ORF Size (bp)
1398 bp
RefSeq ID
NM_053281
RefSeq Synonyms
NM_053281, NM_001139515, NM_001139514, BC114950,
Species
human
UniGene ID
Hs.86603

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.