human CASP8AP2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CASP8AP2.
shAAV-204125
AAV-h-CASP8AP2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CASP8AP2 (caspase 8 associated protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CED-4; FLASH; RIP25
Description (Vector)
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
Gene ID
9994
Gene Name (Vector)
caspase 8 associated protein 2
Gene Symbol
CASP8AP2
HGNC ID
HGNC:1510
ORF Size (aa)
5946
ORF Size (bp)
5946 bp
RefSeq ID
NM_012115
RefSeq Synonyms
NM_012115, NM_001137668, NM_001137667, BC150274, BC132830, BC132828,
Species
human
UniGene ID
Hs.558218
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.