mouse CASP8AP2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Casp8ap2.
shADV-254564
Ad-m-CASP8AP2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Casp8ap2 (caspase 8 associated protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
D4Ertd659e; FLASH
Description (Vector)
Participates in TNF-alpha-induced blockade of glucocorticoid receptor (GR) transactivation at the nuclear receptor coactivator level, upstream and independently of NF-kappa-B. Suppresses both NCOA2- and NCOA3-induced enhancement of GR transactivation. Involved in TNF-alpha-induced activation of NF-kappa-B via a TRAF2-dependent pathway. Acts as a downstream mediator for CASP8-induced activation of NF-kappa-B. Required for the activation of CASP8 in FAS-mediated apoptosis. Required for histone gene transcription and progression through S phase.
Gene ID
26885
Gene Name (Vector)
caspase 8 associated protein 2
Gene Symbol
Casp8ap2
ORF Size (aa)
5889
ORF Size (bp)
5889 bp
RefSeq ID
NM_011997
RefSeq Synonyms
NM_011997, NM_001122978, BC138041, BC138022,
Species
mouse
UniGene ID
Mm.22279
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.