human CACNA1G shRNA silencing AAV

Name
AAV-h-CACNA1G-shRNA

Cat No
shAAV-203903

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CACNA1G.

shAAV-203903

AAV-h-CACNA1G-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CACNA1G (calcium voltage-gated channel subunit alpha1 G). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Ca(V)T.1; Cav3.1; NBR13; SCA42

Description (Vector)

Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene ID

8913

Gene Name (Vector)

calcium voltage-gated channel subunit alpha1 G

Gene Symbol

CACNA1G

HGNC ID

HGNC:1394

ORF Size (aa)

6786

ORF Size (bp)

6786 bp

RefSeq ID

NM_018896

RefSeq Synonyms

NM_198397, NM_198396, NM_198388, NM_198387, NM_198386, NM_198385, NM_198384, NM_198383, NM_198382, NM_198380, NM_198379, NM_198378, NM_198377, NM_198376, NM_018896, NM_001256361, NM_001256360, NM_001256359, NM_001256334, NM_001256333, NM_001256332, NM_001256331, NM_001256330, NM_001256329, NM_001256328, NM_001256327, NM_001256326, NM_001256325, NM_001256324, BC110995,

Species

human

UniGene ID

Hs.591169

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.