human C8A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human C8A.
shAAV-203711
AAV-h-C8A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human C8A (complement C8 alpha chain). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
C8 is a component of the complement system and contains three polypeptides, alpha, beta and gamma. This gene encodes the alpha subunit of C8. C8 participates in the formation of the membrane attack complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause complement C8 alpha-gamma deficiency.
Gene ID
731
Gene Name (Vector)
complement C8 alpha chain
Gene Symbol
C8A
HGNC ID
HGNC:1352
ORF Size (aa)
1755
ORF Size (bp)
1755 bp
RefSeq ID
NM_000562
RefSeq Synonyms
NM_000562, BC132913, BC132911,
Species
human
UniGene ID
Hs.93210
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.