human C3 shRNA silencing AAV

Name
AAV-h-C3-shRNA

Cat No
shAAV-203359

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human C3.

shAAV-203359

AAV-h-C3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human C3 (complement C3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AHUS5; ARMD9; ASP; C3a; C3b; CPAMD1; HEL-S-62p

Description (Vector)

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection.

Gene ID

718

Gene Name (Vector)

complement C3

Gene Symbol

HGNC ID

HGNC:1318

ORF Size (aa)

4992

ORF Size (bp)

4992 bp

RefSeq ID

NM_000064

RefSeq Synonyms

NM_000064, BC150200, BC150179,

Species

human

UniGene ID

Hs.529053

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.