human C1QB shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human C1QB.
shAAV-203133
AAV-h-C1QB-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human C1QB (complement C1q B chain). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
C1QB encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. C1QB encodes the B-chain polypeptide of human complement subcomponent C1q
Gene ID
713
Gene Name (Vector)
complement C1q B chain
Gene Symbol
C1QB
HGNC ID
HGNC:1242
ORF Size (aa)
762
ORF Size (bp)
762 bp
RefSeq ID
NM_000491
RefSeq Synonyms
NM_000491, BC008983,
Species
human
UniGene ID
Hs.8986
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.