human C13ORF3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SKA3.
shAAV-202604
AAV-h-C13ORF3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SKA3 (spindle and kinetochore associated complex subunit 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C13orf3; RAMA1; spindle and kinetochore-associated protein 3
Description (eCommerce)
Spindle and kinetochore associated complex subunit (SKA3) is a component of the spindle and kinetochore-associated protein complex that regulates microtubule attachment to the kinetochores during mitosis. SKA3 localizes to the outer kinetechore and may be required for normal chromosome segregation and cell division [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8IX90].
Description (Vector)
SKA3 encodes a component of the spindle and kinetochore-associated protein complex that regulates microtubule attachment to the kinetochores during mitosis. The encoded protein localizes to the outer kinetechore and may be required for normal chromosome segregation and cell division. Alternative splicing results in multiple transcript variants.
Gene ID
221150
Gene Name (eCommerce)
spindle and kinetochore associated complex subunit 3
Gene Name (Vector)
spindle and kinetochore associated complex subunit 3
Gene Symbol
SKA3
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1239
ORF Size (bp)
1239 bp
Protein Name (eCommerce)
Spindle and kinetochore-associated protein 3
RefSeq ID
NM_145061
RefSeq Synonyms
NM_145061, NM_001166017, BC048988, BC013418,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
Spindle and kinetochore associated complex subunit (SKA3) is a component of the spindle and kinetochore-associated protein complex that regulates microtubule attachment to the kinetochores during mitosis. SKA3 localizes to the outer kinetechore and may be required for normal chromosome segregation and cell division [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8IX90].
UniGene ID
Hs.88523
UniProt ID (eCommerce)
Q8IX90
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.