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mouse F630043A04RIK shRNA silencing AAV

Name 
AAV-m-F630043A04RIK-shRNA
Cat No 
shAAV-258847
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ska3.

shAAV-258847
AAV-m-F630043A04RIK-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ska3 (spindle and kinetochore associated complex subunit 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
F630043A04Rik
Description (Vector)
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule-stimulated oligomerization.
Gene ID
219114
Gene Name (Vector)
spindle and kinetochore associated complex subunit 3
Gene Symbol
Ska3
ORF Size (aa)
1236
ORF Size (bp)
1236 bp
RefSeq ID
NM_198605
RefSeq Synonyms
NM_198605, BC117501, BC117500,
Species
mouse
UniGene ID
Mm.30173

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.