human BPGM shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human BPGM.
shAAV-202237
AAV-h-BPGM-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human BPGM (bisphosphoglycerate mutase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DPGM
Description (Vector)
2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Gene ID
669
Gene Name (Vector)
bisphosphoglycerate mutase
Gene Symbol
BPGM
HGNC ID
HGNC:1093
ORF Size (aa)
780
ORF Size (bp)
780 bp
RefSeq ID
NM_001724
RefSeq Synonyms
NM_199186, NM_001724, NM_001293085, BC017050,
Species
human
UniGene ID
Hs.198365
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.