human BMX shRNA silencing AAV

Name
AAV-h-BMX-shRNA

Cat No
shAAV-202208

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human BMX.

shAAV-202208

AAV-h-BMX-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BMX (BMX non-receptor tyrosine kinase). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ETK; PSCTK2; PSCTK3

Description (Vector)

BMX encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene ID

660

Gene Name (Vector)

BMX non-receptor tyrosine kinase

Gene Symbol

BMX

HGNC ID

HGNC:1079

ORF Size (aa)

2028

ORF Size (bp)

2028 bp

RefSeq ID

NM_001721

RefSeq Synonyms

NM_203281, NM_001721, NM_001320866, BC016652,

Species

human

UniGene ID

Hs.495731

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.