human BLVRB shRNA silencing AAV

Name 
AAV-h-BLVRB-shRNA
Cat No 
shAAV-202174
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human BLVRB.

shAAV-202174
AAV-h-BLVRB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BLVRB (biliverdin reductase B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Biliverdin reductase B; biliverdin-IX beta-reductase; BVRB; BVR-B; epididymis secretory protein Li 10; flavin reductase (NADPH); FLR; FR; GHBP; green heme-binding protein; HEL-S-10; NADPH; NADPH-dependent diaphorase; NADPH-flavin reductase; SDR43U1; short chain dehydrogenase/reductase family 43U, member 1
Description (eCommerce)
The final step in heme metabolism in mammals is catalyzed by the cytosolic biliverdin reductase enzymes A and B (EC 1.3.1.24) [taken from NCBI Entrez Gene (Gene ID: 645)].
Description (Vector)
The final step in heme metabolism in mammals is catalyzed by the cytosolic biliverdin reductase enzymes A and B (EC 1.3.1.24).(supplied by OMIM, Jul 2009)
Gene ID
645
Gene Name (eCommerce)
biliverdin reductase B
Gene Name (Vector)
biliverdin reductase B
Gene Symbol
BLVRB
HGNC ID
HGNC:1063
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
621
Protein Name (eCommerce)
Flavin reductase
RefSeq ID
NM_000713
RefSeq Synonyms
NM_000713, BC109371,
Research Areas
Immunology,Interleukin Signaling,Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,immunology,metabolism,signal_transduction
Species
human
Target Sentence
The final step in heme metabolism in mammals is catalyzed by the cytosolic biliverdin reductase enzymes A and B (EC 1.3.1.24) [taken from NCBI Entrez Gene (Gene ID: 645)].
UniGene ID
Hs.515785
UniProt ID (eCommerce)
P30043

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.