human BEST4 shRNA silencing AAV

Name 
AAV-h-BEST4-shRNA
Cat No 
shAAV-202101
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human BEST4.

shAAV-202101
AAV-h-BEST4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BEST4 (bestrophin 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
VMD2L2
Description (Vector)
BEST4 is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 4 gene is predominantly expressed in the colon.
Gene ID
266675
Gene Name (Vector)
bestrophin 4
Gene Symbol
BEST4
HGNC ID
HGNC:17106
ORF Size (aa)
1422
ORF Size (bp)
1422 bp
RefSeq ID
NM_153274
RefSeq Synonyms
NM_153274, BC101823,
Species
human
UniGene ID
Hs.302513

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.