human ATP6AP2 shRNA silencing AAV

Name
AAV-h-ATP6AP2-shRNA

Cat No
shAAV-201741

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human ATP6AP2.

shAAV-201741

AAV-h-ATP6AP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ATP6AP2 (ATPase H+ transporting accessory protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

APT6M8-9; ATP6IP2; ATP6M8-9; ELDF10; HT028; M8-9; MRXE; MRXSH; MSTP009; PRR; RENR; XMRE; XPDS

Description (Vector)

ATP6AP2 encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases.

Gene ID

10159

Gene Name (Vector)

ATPase H+ transporting accessory protein 2

Gene Symbol

ATP6AP2

HGNC ID

HGNC:18305

ORF Size (aa)

1053

ORF Size (bp)

1053 bp

RefSeq ID

NM_005765

RefSeq Synonyms

NM_005765, BC084541, BC010395,

Species

human

UniGene ID

Hs.495960

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.