human ARL6 shRNA silencing AAV

Name
AAV-h-ARL6-shRNA

Cat No
shAAV-201411

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human ARL6.

shAAV-201411

AAV-h-ARL6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ARL6 (ADP ribosylation factor like GTPase 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BBS3; RP55

Description (Vector)

ARL6 belongs to the ARF family of GTP-binding proteins. ARF proteins are important regulators of cellular traffic and are the founding members of an expanding family of homologous proteins and genomic sequences. They depart from other small GTP-binding proteins by a unique structural device that implements front-back communication from the N-terminus to the nucleotide-binding site. Studies of the mouse ortholog of this protein suggest an involvement in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been described.

Gene ID

84100

Gene Name (Vector)

ADP ribosylation factor like GTPase 6

Gene Symbol

ARL6

HGNC ID

HGNC:13210

ORF Size (aa)

561

ORF Size (bp)

561 bp

RefSeq ID

NM_032146

RefSeq Synonyms

NM_177976, NM_032146, NM_001323514, NM_001323513, NM_001278293, BC024239,

Species

human

UniGene ID

Hs.373801

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.