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human CTSE Over-expression AAV

Name 
AAV-h-CTSE
Cat No 
AAV-206268
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CTSE.

AAV-206268
AAV-h-CTSE

Ready-to-use AAV expressing Human CTSE (cathepsin E). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CATE
Description (Vector)
CTSE is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene.
Gene ID
1510
Gene Name (Vector)
cathepsin E
Gene Symbol
CTSE
HGNC ID
HGNC:2530
ORF Size (aa)
1191
ORF Size (bp)
1191 bp
RefSeq ID
NM_001910
RefSeq Synonyms
NM_148964, NM_001910, NM_001317331, BC042537,
Species
human
UniGene ID
Hs.644082

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.