human ALG12 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ALG12.
shAAV-200770
AAV-h-ALG12-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ALG12 (ALG12, alpha-1,6-mannosyltransferase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CDG1G; ECM39; hALG12; PP14673
Description (Vector)
ALG12 encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation.
Gene ID
79087
Gene Name (Vector)
ALG12, alpha-1,6-mannosyltransferase
Gene Symbol
ALG12
HGNC ID
HGNC:19358
ORF Size (aa)
1467
ORF Size (bp)
1467 bp
RefSeq ID
NM_024105
RefSeq Synonyms
NM_024105, BC098562, BC001729,
Species
human
UniGene ID
Hs.526711
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.