AAV with TBG promoter driven TdTomato
This AAV expresses TdTomato driven by a liver TBG promoter.
TBG is a 0.8kb hybrid promoter based on the human thyroid hormone-binding globulin (TBG) promoter and microglobin/bikunin enhancer. This hybrid promoter has been used for liver-specific transgene expression.
dTomato belongs to a family of fluorescent proteins called mFruit. Two dTomato units were joined head-to-tail through a linker, yielding a tandem dimer fluorescent protein, tdTomato. The tdTomato derivative is the brightest fluorescent protein yet reported, featuring an orange-red emission maximum at 581nm and is one of the most photo-stable fluorescent proteins. Other fluorescent proteins with similar emission spectra include DsRed, DsRed2, TurboRFP, TagRFP, and TagRFP-T.
Ready-to-use AAV expressing TdTomato driven by a liver TBG promoter. Available in AAV1, AAV2, AAV5, AAV6, AAV8, AAV9, AAV-DJ and other serotypes.