rat GOSR1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Gosr1.
shADV-295139
Ad-r-GOSR1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Gosr1 (golgi SNAP receptor complex member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GOS28; p28
Description (Vector)
Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
Gene ID
94189
Gene Name (Vector)
golgi SNAP receptor complex member 1
Gene Symbol
Gosr1
ORF Size (aa)
753
ORF Size (bp)
753 bp
RefSeq ID
NM_053584
RefSeq Synonyms
NM_053584, BC126068,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.