rat RAD18 shRNA silencing Adenovirus

Name 
Ad-r-RAD18-shRNA
Cat No 
shADV-295111
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Rad18.

shADV-295111
Ad-r-RAD18-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Rad18 (RAD18 E3 ubiquitin protein ligase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
61
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity.
Gene ID
362412
Gene Name (Vector)
RAD18 E3 ubiquitin protein ligase
Gene Symbol
Rad18
ORF Size (aa)
1485
ORF Size (bp)
1485 bp
RefSeq ID
NM_001077673
RefSeq Synonyms
NM_001077673, BC127510,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.