rat RGD1306772 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Rita1.
shADV-294751
Ad-r-RGD1306772-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Rita1 (RBPJ interacting and tubulin associated 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RGD1306772; Rita
Description (Vector)
Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.
Gene ID
288683
Gene Name (Vector)
RBPJ interacting and tubulin associated 1
Gene Symbol
Rita1
ORF Size (aa)
777
RefSeq ID
NM_001044226
RefSeq Synonyms
NM_001044226, BC112384,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.