rat PCBP2 shRNA silencing Adenovirus

Name
Ad-r-PCBP2-shRNA

Cat No
shADV-294693

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Pcbp2.

shADV-294693

Ad-r-PCBP2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Pcbp2 (poly(rC) binding protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

100

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)

Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitinationa and degradation.

Gene ID

363005

Gene Name (Vector)

poly(rC) binding protein 2

Gene Symbol

Pcbp2

ORF Size (aa)

1008

RefSeq ID

NM_001013223

RefSeq Synonyms

NM_001013223, BC097410, BC078909, BC078906,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.