rat YBX1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Ybx1.
shADV-294468
Ad-r-YBX1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Ybx1 (Y box binding protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Byb1; Cbfa; Dbpb; Ef1a; Msy1; Nsep1; Yb1
Description (Vector)
Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro|Function: The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation.
Gene ID
500538
Gene Name (Vector)
Y box binding protein 1
Gene Symbol
Ybx1
ORF Size (aa)
981
ORF Size (bp)
981 bp
RefSeq ID
NM_031563
RefSeq Synonyms
NM_031563, BC103637, BC098672, BC072486,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.