rat MGC114529 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Magec2.
shADV-293958
Ad-r-MGC114529-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Magec2 (MAGE family member C2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.
Gene ID
317590
Gene Name (Vector)
MAGE family member C2
Gene Symbol
Magec2
ORF Size (aa)
1290
ORF Size (bp)
1290 bp
RefSeq ID
NM_001025713
RefSeq Synonyms
NM_001025713, BC097464,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.