rat THAP1 shRNA silencing Adenovirus

Name
Ad-r-THAP1-shRNA

Cat No
shADV-293833

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Thap1.

shADV-293833

Ad-r-THAP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Thap1 (THAP domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)

DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.

Gene ID

306547

Gene Name (Vector)

THAP domain containing 1

Gene Symbol

Thap1

ORF Size (aa)

633

ORF Size (bp)

633 bp

RefSeq ID

NM_001008340

RefSeq Synonyms

NM_001008340, BC086347,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.