rat USP2 shRNA silencing Adenovirus

Name
Ad-r-USP2-shRNA

Cat No
shADV-293786

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Usp2.

shADV-293786

Ad-r-USP2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Usp2 (ubiquitin specific peptidase 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

UBP-t

Description (Vector)

Hydrolase that deubiquitinates polyubiquitinated target proteins such as MDM2, MDM4 and CCND1. Isoform 1 and isoform 4 possess both ubiquitin-specific peptidase and isopeptidase activities. Deubiquitinates MDM2 without reversing MDM2-mediated p53/TP53 ubiquitination and thus indirectly promotes p53/TP53 degradation and limits p53 activity. Has no deubiquitinase activity against p53/TP53. Prevents MDM2-mediated degradation of MDM4. Plays a role in the G1/S cell-cycle progression in normal and cancer cells. Plays a role in the regulation of myogenic differentiation of embryonic muscle cells.

Gene ID

115771

Gene Name (Vector)

ubiquitin specific peptidase 2

Gene Symbol

Usp2

ORF Size (aa)

1857

ORF Size (bp)

1857 bp

RefSeq ID

NM_053774

RefSeq Synonyms

NM_053774, BC085719,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.