rat NRP1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Nrp1.
shADV-293769
Ad-r-NRP1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Nrp1 (neuropilin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Nrp
Description (Vector)
The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis|Function: The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.
Gene ID
246331
Gene Name (Vector)
neuropilin 1
Gene Symbol
Nrp1
ORF Size (aa)
2769
ORF Size (bp)
2769 bp
RefSeq ID
NM_145098
RefSeq Synonyms
NM_145098, BC085689,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.