rat MTM1 shRNA silencing Adenovirus

Name
Ad-r-MTM1-shRNA

Cat No
shADV-293407

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Mtm1.

shADV-293407

Ad-r-MTM1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Mtm1 (myotubularin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)

Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis.

Gene ID

288762

Gene Name (Vector)

myotubularin 1

Gene Symbol

Mtm1

ORF Size (aa)

1662

ORF Size (bp)

1662 bp

RefSeq ID

NM_001013047

RefSeq Synonyms

NM_001013047, BC091225,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.