rat CENPT shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Cenpt.
shADV-293373
Ad-r-CENPT-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Cenpt (centromere protein T). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RGD1309383
Description (Vector)
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPT has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis.
Gene ID
307805
Gene Name (Vector)
centromere protein T
Gene Symbol
Cenpt
ORF Size (aa)
1557
ORF Size (bp)
1557 bp
RefSeq ID
NM_001024257
RefSeq Synonyms
NM_001024257, BC093396,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.