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rat HFE2 shRNA silencing Adenovirus

Name 
Ad-r-HFE2-shRNA
Cat No 
shADV-293238
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Hfe2.

shADV-293238
Ad-r-HFE2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Hfe2 (hemochromatosis type 2 (juvenile)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Rgmc
Description (Vector)
Member of the repulsive guidance molecule (RGM) family. Involved in iron metabolism. Acts as a bone morphogenetic protein (BMP) coreceptor (By similarity). Enhancement of BMP signaling regulates hepcidin (HAMP) expression and iron metabolism (By similarity). May cooperate with hepcidin to restrict iron absorption in the gut. Could represent the cellular receptor for hepcidin.
Gene ID
310681
Gene Name (Vector)
hemochromatosis type 2 (juvenile)
Gene Symbol
Hfe2
ORF Size (aa)
1269
ORF Size (bp)
1269 bp
RefSeq ID
NM_001012080
RefSeq Synonyms
NM_001012080, BC089203,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.