rat KMO shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Kmo.
shADV-292712
Ad-r-KMO-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Kmo (kynurenine 3-monooxygenase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
Gene ID
59113
Gene Name (Vector)
kynurenine 3-monooxygenase
Gene Symbol
Kmo
ORF Size (aa)
1437
ORF Size (bp)
1437 bp
RefSeq ID
NM_021593
RefSeq Synonyms
NM_021593, BC088142,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.