rat NDN shRNA silencing Adenovirus

Name
Ad-r-NDN-shRNA

Cat No
shADV-292596

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Ndn.

shADV-292596

Ad-r-NDN-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Ndn (necdin, MAGE family member). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)

Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle-promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences (By similarity).

Gene ID

308690

Gene Name (Vector)

necdin, MAGE family member

Gene Symbol

Ndn

ORF Size (aa)

978

ORF Size (bp)

978 bp

RefSeq ID

NM_001008558

RefSeq Synonyms

NM_001008558, BC087630,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.